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BMCBI
2008
164views more  BMCBI 2008»
14 years 9 months ago
MeInfoText: associated gene methylation and cancer information from text mining
Background: DNA methylation is an important epigenetic modification of the genome. Abnormal DNA methylation may result in silencing of tumor suppressor genes and is common in a va...
Yu-Ching Fang, Hsuan-Cheng Huang, Hsueh-Fen Juan
GECCO
2005
Springer
156views Optimization» more  GECCO 2005»
15 years 3 months ago
Extraction of informative genes from microarray data
Identification of those genes that might anticipate the clinical behavior of different types of cancers is challenging due to availability of a smaller number of patient samples...
Topon Kumar Paul, Hitoshi Iba
BMCBI
2008
113views more  BMCBI 2008»
14 years 9 months ago
SynBlast: Assisting the analysis of conserved synteny information
Motivation: In the last years more than 20 vertebrate genomes have been sequenced, and the rate at which genomic DNA information becomes available is rapidly accelerating. Gene du...
Jörg Lehmann, Peter F. Stadler, Sonja J. Proh...
BMCBI
2007
128views more  BMCBI 2007»
14 years 9 months ago
Model order selection for bio-molecular data clustering
Background: Cluster analysis has been widely applied for investigating structure in bio-molecular data. A drawback of most clustering algorithms is that they cannot automatically ...
Alberto Bertoni, Giorgio Valentini
BIBM
2009
IEEE
172views Bioinformatics» more  BIBM 2009»
15 years 2 months ago
Identifying Gene Signatures from Cancer Progression Data Using Ordinal Analysis
—A comprehensive understanding of cancer progression may shed light on genetic and molecular mechanisms of oncogenesis, and it may provide much needed information for effective d...
Yoon Soo Pyon, Jing Li