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179
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BMCBI
2010
15 years 6 months ago
2010
Background: New "next generation" DNA sequencing technologies offer individual researchers the ability to rapidly generate large amounts of genome sequence data at drama...
143
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BMCBI
2010
15 years 6 months ago
2010
Background: High-throughput automated sequencing has enabled an exponential growth rate of sequencing data. This requires increasing sequence quality and reliability in order to a...
143
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BMCBI
2010
15 years 6 months ago
2010
Background: Knowledge-based potentials have been widely used in the last 20 years for fold recognition, protein structure prediction from amino acid sequence, ligand binding, prot...
176
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BMCBI
2007
15 years 6 months ago
2007
Background: Most human genes produce several transcripts with different exon contents by using alternative promoters, alternative polyadenylation sites and alternative splice site...
170
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BMCBI
2007
15 years 6 months ago
2007
Background: Detailed information on DNA-binding transcription factors (the key players in the regulation of gene expression) and on transcriptional regulatory interactions of micr...