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118
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BMCBI
2010
151views more  BMCBI 2010»
15 years 22 days ago
Using diffusion distances for flexible molecular shape comparison
Background: Many molecules are flexible and undergo significant shape deformation as part of their function, and yet most existing molecular shape comparison (MSC) methods treat t...
Yu-Shen Liu, Qi Li, Guo-Qin Zheng, Karthik Ramani,...
BMCBI
2008
173views more  BMCBI 2008»
15 years 22 days ago
Gene Vector Analysis (Geneva): A unified method to detect differentially-regulated gene sets and similar microarray experiments
Background: Microarray experiments measure changes in the expression of thousands of genes. The resulting lists of genes with changes in expression are then searched for biologica...
Stephen W. Tanner, Pankaj Agarwal
126
Voted
BMCBI
2007
176views more  BMCBI 2007»
15 years 22 days ago
The Firegoose: two-way integration of diverse data from different bioinformatics web resources with desktop applications
Background: Information resources on the World Wide Web play an indispensable role in modern biology. But integrating data from multiple sources is often encumbered by the need to...
J. Christopher Bare, Paul T. Shannon, Amy K. Schmi...
103
Voted
BMCBI
2008
135views more  BMCBI 2008»
15 years 22 days ago
Ab-origin: an enhanced tool to identify the sourcing gene segments in germline for rearranged antibodies
Background: In the adaptive immune system, variable regions of immunoglobulin (IG) are encoded by random recombination of variable (V), diversity (D), and joining (J) gene segment...
Xiaojing Wang, Di Wu, SiYuan Zheng, Jing Sun, Lin ...
KAIS
2006
110views more  KAIS 2006»
15 years 17 days ago
Multi-step density-based clustering
Abstract. Data mining in large databases of complex objects from scientific, engineering or multimedia applications is getting more and more important. In many areas, complex dista...
Stefan Brecheisen, Hans-Peter Kriegel, Martin Pfei...
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