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RECOMB
2010
Springer
15 years 1 months ago
Algorithms for Detecting Significantly Mutated Pathways in Cancer
Abstract. Recent genome sequencing studies have shown that the somatic mutations that drive cancer development are distributed across a large number of genes. This mutational heter...
Fabio Vandin, Eli Upfal, Benjamin J. Raphael
BMCBI
2005
102views more  BMCBI 2005»
14 years 11 months ago
Modelling the interaction of steroid receptors with endocrine disrupting chemicals
Background: The organic polychlorinated compounds like dichlorodiphenyltrichloroethane with its metabolites and polychlorinated biphenyls are a class of highly persistent environm...
Pasqualina D'Ursi, Erika Salvi, Paola Fossa, Lucia...
BMCBI
2006
160views more  BMCBI 2006»
14 years 11 months ago
MIMAS: an innovative tool for network-based high density oligonucleotide microarray data management and annotation
Background: The high-density oligonucleotide microarray (GeneChip) is an important tool for molecular biological research aiming at large-scale detection of small nucleotide polym...
Leandro Hermida, Olivier Schaad, Philippe Demougin...
DEXAW
2004
IEEE
80views Database» more  DEXAW 2004»
15 years 3 months ago
Traceable Document Flows
Ad-hoc data exchange, e.g., by sending email attachments, leads to multiple copies or versions of a document at dispersed nodes in a network. However, their relationships such as ...
Martin Bernauer, Gerti Kappel, Elke Michlmayr
RECOMB
1999
Springer
15 years 4 months ago
Evolution of metabolisms: a new method for the comparison of metabolic pathways
The abundance of information provided by completely sequenced genomes de nes a starting point for new insights in the multilevel organization of organisms and their evolution. At ...
Christian V. Forst, Klaus Schulten