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» Multiple Genome Alignment by Clustering Pairwise Matches
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86
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ECCB
2008
IEEE
15 years 4 months ago
Connect the dots: exposing hidden protein family connections from the entire sequence tree
Motivation: Mapping of remote evolutionary links is a classic computational problem of much interest. Relating protein families allows for functional and structural inference on u...
Yaniv Loewenstein, Michal Linial
BMCBI
2010
155views more  BMCBI 2010»
14 years 7 months ago
BrEPS: a flexible and automatic protocol to compute enzyme-specific sequence profiles for functional annotation
Background: Models for the simulation of metabolic networks require the accurate prediction of enzyme function. Based on a genomic sequence, enzymatic functions of gene products a...
Constantin Bannert, A. Welfle, C. aus dem Spring, ...
BMCBI
2004
106views more  BMCBI 2004»
14 years 9 months ago
Spotting effect in microarray experiments
Background: Microarray data must be normalized because they suffer from multiple biases. We have identified a source of spatial experimental variability that significantly affects...
Tristan Mary-Huard, Jean-Jacques Daudin, Sté...
69
Voted
APBC
2004
108views Bioinformatics» more  APBC 2004»
14 years 11 months ago
Ladderlike Stepping and Interval Jumping Searching Algorithms for DNA Sequences
In this study we have designed a novel algorithm for searching common segments in multiple DNA sequences. To improve efficiency in pattern searching, combination of hashing encodi...
Tun-Wen Pai, Margaret Dah-Tsyr Chang, Jia-Han Chu,...
BMCBI
2006
144views more  BMCBI 2006»
14 years 9 months ago
More robust detection of motifs in coexpressed genes by using phylogenetic information
Background: Several motif detection algorithms have been developed to discover overrepresented motifs in sets of coexpressed genes. However, in a noisy gene list, the number of ge...
Pieter Monsieurs, Gert Thijs, Abeer A. Fadda, Sigr...