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RECOMB
2005
Springer
16 years 6 days ago
Causal Inference of Regulator-Target Pairs by Gene Mapping of Expression Phenotypes
Background: Correlations between polymorphic markers and observed phenotypes provide the basis for mapping traits in quantitative genetics. When the phenotype is gene expression, ...
David Kulp, Manjunatha Jagalur
RECOMB
2004
Springer
16 years 6 days ago
Predicting Genetic Regulatory Response Using Classification: Yeast Stress Response
We present a novel classification-based algorithm called GeneClass for learning to predict gene regulatory response. Our approach is motivated by the hypothesis that in simple orga...
Manuel Middendorf, Anshul Kundaje, Chris Wiggins, ...
STOC
2007
ACM
142views Algorithms» more  STOC 2007»
16 years 6 days ago
Lower bounds for randomized read/write stream algorithms
Motivated by the capabilities of modern storage architectures, we consider the following generalization of the data stream model where the algorithm has sequential access to multi...
Paul Beame, T. S. Jayram, Atri Rudra
STOC
2006
ACM
129views Algorithms» more  STOC 2006»
16 years 6 days ago
Optimal phylogenetic reconstruction
One of the major tasks of evolutionary biology is the reconstruction of phylogenetic trees from molecular data. The evolutionary model is given by a Markov chain on the true evolu...
Constantinos Daskalakis, Elchanan Mossel, Sé...
SIGMOD
2008
ACM
95views Database» more  SIGMOD 2008»
16 years 1 days ago
Interactive generation of integrated schemas
Schema integration is the problem of creating a unified target schema based on a set of existing source schemas that relate to each other via specified correspondences. The unifie...
Laura Chiticariu, Phokion G. Kolaitis, Lucian Popa