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BMCBI
2006
166views more  BMCBI 2006»
15 years 3 months ago
SEQOPTICS: a protein sequence clustering system
Background: Protein sequence clustering has been widely used as a part of the analysis of protein structure and function. In most cases single linkage or graph-based clustering al...
Yonghui Chen, Kevin D. Reilly, Alan P. Sprague, Zh...
BMCBI
2006
242views more  BMCBI 2006»
15 years 3 months ago
Predicting residue-wise contact orders in proteins by support vector regression
Background: The residue-wise contact order (RWCO) describes the sequence separations between the residues of interest and its contacting residues in a protein sequence. It is a ne...
Jiangning Song, Kevin Burrage
BMCBI
2006
153views more  BMCBI 2006»
15 years 3 months ago
Intensity-based hierarchical Bayes method improves testing for differentially expressed genes in microarray experiments
Background: The small sample sizes often used for microarray experiments result in poor estimates of variance if each gene is considered independently. Yet accurately estimating v...
Maureen A. Sartor, Craig R. Tomlinson, Scott C. We...
BMCBI
2006
126views more  BMCBI 2006»
15 years 3 months ago
Genomes as geography: using GIS technology to build interactive genome feature maps
Background: Many commonly used genome browsers display sequence annotations and related attributes as horizontal data tracks that can be toggled on and off according to user prefe...
Mary E. Dolan, Constance C. Holden, M. Kate Beard,...
BMCBI
2006
139views more  BMCBI 2006»
15 years 3 months ago
Integrated functional visualization of eukaryotic genomes
Background: Increasing amounts of data from large scale whole genome analysis efforts demands convenient tools for manipulation, visualization and investigation. Whole genome plot...
Rohit Ghai, Hannes Lindemann, Trinad Chakraborty
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