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BMCBI
2006
124views more  BMCBI 2006»
15 years 3 months ago
The development and validation of the Virtual Tissue Matrix, a software application that facilitates the review of tissue microa
Background: The Tissue Microarray (TMA) facilitates high-throughput analysis of hundreds of tissue specimens simultaneously. However, bottlenecks in the storage and manipulation o...
Catherine M. Conway, Deirdre O'Shea, Sallyann O'Br...
BMCBI
2006
94views more  BMCBI 2006»
15 years 3 months ago
Novel knowledge-based mean force potential at the profile level
Background: The development and testing of functions for the modeling of protein energetics is an important part of current research aimed at understanding protein structure and f...
Qiwen Dong, Xiaolong Wang, Lei Lin
BMCBI
2006
166views more  BMCBI 2006»
15 years 3 months ago
bioNMF: a versatile tool for non-negative matrix factorization in biology
Background: In the Bioinformatics field, a great deal of interest has been given to Non-negative matrix factorization technique (NMF), due to its capability of providing new insig...
Alberto D. Pascual-Montano, Pedro Carmona-Saez, Mo...
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BMCBI
2006
115views more  BMCBI 2006»
15 years 3 months ago
AgdbNet - antigen sequence database software for bacterial typing
Background: Bacterial typing schemes based on the sequences of genes encoding surface antigens require databases that provide a uniform, curated, and widely accepted nomenclature ...
Keith A. Jolley, Martin C. J. Maiden
BMCBI
2006
137views more  BMCBI 2006»
15 years 3 months ago
Genome BLAST distance phylogenies inferred from whole plastid and whole mitochondrion genome sequences
Background: Phylogenetic methods which do not rely on multiple sequence alignments are important tools in inferring trees directly from completely sequenced genomes. Here, we exte...
Alexander F. Auch, Stefan R. Henz, Barbara R. Holl...
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