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BMCBI
2007
166views more  BMCBI 2007»
15 years 3 months ago
How to decide which are the most pertinent overly-represented features during gene set enrichment analysis
Background: The search for enriched features has become widely used to characterize a set of genes or proteins. A key aspect of this technique is its ability to identify correlati...
Roland Barriot, David J. Sherman, Isabelle Dutour
BMCBI
2007
106views more  BMCBI 2007»
15 years 3 months ago
Discovering functional linkages and uncharacterized cellular pathways using phylogenetic profile comparisons: a comprehensive as
Background: A widely-used approach for discovering functional and physical interactions among proteins involves phylogenetic profile comparisons (PPCs). Here, proteins with simila...
Raja Jothi, Teresa M. Przytycka, L. Aravind
BMCBI
2007
111views more  BMCBI 2007»
15 years 3 months ago
MotifCombinator: a web-based tool to search for combinations of cis-regulatory motifs
Background: A combination of multiple types of transcription factors and cis-regulatory elements is often required for gene expression in eukaryotes, and the combinatorial regulat...
Mamoru Kato, Tatsuhiko Tsunoda
BMCBI
2007
218views more  BMCBI 2007»
15 years 3 months ago
Annotation and query of tissue microarray data using the NCI Thesaurus
Background: The Stanford Tissue Microarray Database (TMAD) is a repository of data serving a consortium of pathologists and biomedical researchers. The tissue samples in TMAD are ...
Nigam H. Shah, Daniel L. Rubin, Inigo Espinosa, Ke...
BMCBI
2007
120views more  BMCBI 2007»
15 years 3 months ago
Quantitative sequence-function relationships in proteins based on gene ontology
Background: The relationship between divergence of amino-acid sequence and divergence of function among homologous proteins is complex. The assumption that homologs share function...
Vineet Sangar, Daniel J. Blankenberg, Naomi Altman...
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