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NAR
2007
152views more  NAR 2007»
14 years 11 months ago
COMPASS server for remote homology inference
COMPASS is a method for homology detection and local alignment construction based on the comparison of multiple sequence alignments (MSAs). The method derives numerical profiles f...
Ruslan Sadreyev, Ming Tang, Bong-Hyun Kim, Nick V....
BMCBI
2008
78views more  BMCBI 2008»
14 years 11 months ago
A new protein linear motif benchmark for multiple sequence alignment software
Background: Linear motifs (LMs) are abundant short regulatory sites used for modulating the functions of many eukaryotic proteins. They play important roles in post-translational ...
Emmanuel Perrodou, Claudia Chica, Olivier Poch, To...
BMCBI
2005
122views more  BMCBI 2005»
14 years 11 months ago
Bayesian coestimation of phylogeny and sequence alignment
Background: Two central problems in computational biology are the determination of the alignment and phylogeny of a set of biological sequences. The traditional approach to this p...
Gerton Lunter, István Miklós, Alexei...
WABI
2005
Springer
117views Bioinformatics» more  WABI 2005»
15 years 5 months ago
Faster Algorithms for Optimal Multiple Sequence Alignment Based on Pairwise Comparisons
Multiple Sequence Alignment (MSA) is one of the most fundamental problems in computational molecular biology. The running time of the best known scheme for finding an optimal ali...
Pankaj K. Agarwal, Yonatan Bilu, Rachel Kolodny
BMCBI
2007
130views more  BMCBI 2007»
14 years 11 months ago
HMM-ModE - Improved classification using profile hidden Markov models by optimising the discrimination threshold and modifying e
Background: Profile Hidden Markov Models (HMM) are statistical representations of protein families derived from patterns of sequence conservation in multiple alignments and have b...
Prashant K. Srivastava, Dhwani K. Desai, Soumyadee...