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» Multiple Sequence Alignment Based on Profile Alignment of In...
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NAR
2006
164views more  NAR 2006»
14 years 11 months ago
FISH - family identification of sequence homologues using structure anchored hidden Markov models
The FISH server is highly accurate in identifying the family membership of domains in a query protein sequence, even in the case of very low sequence identities to known homologue...
Jeanette Tångrot, Lixiao Wang, Bo Kågs...
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BMCBI
2006
94views more  BMCBI 2006»
14 years 11 months ago
Novel knowledge-based mean force potential at the profile level
Background: The development and testing of functions for the modeling of protein energetics is an important part of current research aimed at understanding protein structure and f...
Qiwen Dong, Xiaolong Wang, Lei Lin
BMCBI
2005
100views more  BMCBI 2005»
14 years 11 months ago
EvDTree: structure-dependent substitution profiles based on decision tree classification of 3D environments
Background: Structure-dependent substitution matrices increase the accuracy of sequence alignments when the 3D structure of one sequence is known, and are successful e.g. in fold ...
Jean-Christophe Gelly, Laurent Chiche, Jér&...
BMCBI
2010
129views more  BMCBI 2010»
14 years 12 months ago
Detection of distant evolutionary relationships between protein families using theory of sequence profile-profile comparison
Background: Detection of common evolutionary origin (homology) is a primary means of inferring protein structure and function. At present, comparison of protein families represent...
Mindaugas Margelevicius, Ceslovas Venclovas
NAR
2011
256views Computer Vision» more  NAR 2011»
14 years 2 months ago
ModBase, a database of annotated comparative protein structure models, and associated resources
ModBase (http://salilab.org/modbase) is a database of annotated comparative protein structure models. The models are calculated by ModPipe, an automated modeling pipeline that rel...
Ursula Pieper, Benjamin M. Webb, David T. Barkan, ...