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BIBM
2010
IEEE
144views Bioinformatics» more  BIBM 2010»
14 years 9 months ago
Identification and quantification of abundant species from pyrosequences of 16S rRNA by consensus alignment
16S rRNA gene profiling has recently been boosted by the development of pyrosequencing methods. A common analysis is to group pyrosequences into Operational Taxonomic Units (OTUs),...
Yuzhen Ye
BMCBI
2005
100views more  BMCBI 2005»
14 years 11 months ago
Scoredist: A simple and robust protein sequence distance estimator
Background: Distance-based methods are popular for reconstructing evolutionary trees thanks to their speed and generality. A number of methods exist for estimating distances from ...
Erik L. L. Sonnhammer, Volker Hollich
100
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ECCB
2008
IEEE
15 years 6 months ago
Connect the dots: exposing hidden protein family connections from the entire sequence tree
Motivation: Mapping of remote evolutionary links is a classic computational problem of much interest. Relating protein families allows for functional and structural inference on u...
Yaniv Loewenstein, Michal Linial
VLSISP
2010
119views more  VLSISP 2010»
14 years 6 months ago
Hardware Acceleration of HMMER on FPGAs
We propose a new parallelization scheme for the hmmsearch function of the HMMER software, in order to target FPGA technology. hmmsearch is a very compute intensive software for bio...
Steven Derrien, Patrice Quinton
BMCBI
2010
177views more  BMCBI 2010»
14 years 12 months ago
Clustering of protein families into functional subtypes using Relative Complexity Measure with reduced amino acid alphabets
Background: Phylogenetic analysis can be used to divide a protein family into subfamilies in the absence of experimental information. Most phylogenetic analysis methods utilize mu...
Aydin Albayrak, Hasan H. Otu, Ugur O. Sezerman