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BMCBI
2007
113views more  BMCBI 2007»
14 years 11 months ago
Statistical power of phylo-HMM for evolutionarily conserved element detection
Background: An important goal of comparative genomics is the identification of functional elements through conservation analysis. Phylo-HMM was recently introduced to detect conse...
Xiaodan Fan, Jun Zhu, Eric E. Schadt, Jun S. Liu
BIOCOMP
2007
15 years 1 months ago
Aldose Reductase and Nitric Oxide Synthase Role in Diabetic Retinopathy: A Bioinformatics Study
- Diabetic retinopathy is the leading cause of blindness among patients with diabetes mellitus. We investigated the role of several proteins that are likely to be involved in the d...
Hanuman Thota, Nageswara rao Kunjam, Suresh Babu C...
BMCBI
2010
160views more  BMCBI 2010»
14 years 6 months ago
eHive: An Artificial Intelligence workflow system for genomic analysis
Background: The Ensembl project produces updates to its comparative genomics resources with each of its several releases per year. During each release cycle approximately two week...
Jessica Severin, Kathryn Beal, Albert J. Vilella, ...
BMCBI
2008
142views more  BMCBI 2008»
14 years 11 months ago
Strategies for measuring evolutionary conservation of RNA secondary structures
Background: Evolutionary conservation of RNA secondary structure is a typical feature of many functional non-coding RNAs. Since almost all of the available methods used for predic...
Andreas R. Gruber, Stephan H. F. Bernhart, Ivo L. ...
IMSCCS
2006
IEEE
15 years 5 months ago
Identification of New Members of Hydrophobin Family Using Primary Structure Analysis
Background: Hydrophobins are fungal proteins that can turn into amphipathic membranes at hydrophilic/hydrophobic interfaces by self-assembly. The assemblages by Class I hydrophobi...
Kuan Yang, Youping Deng, Chaoyang Zhang, Mohamed O...