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» Multiple Sequence Alignment Using Reconfigurable Computing
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BMCBI
2011
14 years 4 months ago
PICS-Ord: Unlimited Coding of Ambiguous Regions by Pairwise Identity and Cost Scores Ordination
Background: We present a novel method to encode ambiguously aligned regions in fixed multiple sequence alignments by ‘Pairwise Identity and Cost Scores Ordination’ (PICS-Ord)....
Robert K. Luecking, Brendan P. Hodkinson, Alexandr...
NAR
2007
152views more  NAR 2007»
14 years 9 months ago
COMPASS server for remote homology inference
COMPASS is a method for homology detection and local alignment construction based on the comparison of multiple sequence alignments (MSAs). The method derives numerical profiles f...
Ruslan Sadreyev, Ming Tang, Bong-Hyun Kim, Nick V....
IISWC
2006
IEEE
15 years 3 months ago
Performance Analysis of Sequence Alignment Applications
— Recent advances in molecular biology have led to a continued growth in the biological information generated by the scientific community. Additionally, this area has become a m...
Friman Sánchez, Esther Salamí, Alex ...
BMCBI
2011
14 years 4 months ago
Accurate statistics for local sequence alignment with position-dependent scoring by rare-event sampling
Background: Molecular database search tools need statistical models to assess the significance for the resulting hits. In the classical approach one asks the question how probable...
Stefan Wolfsheimer, Inke Herms, Sven Rahmann, Alex...
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RECOMB
2008
Springer
15 years 10 months ago
Spectrum Fusion: Using Multiple Mass Spectra for De Novo Peptide Sequencing
We report on a new algorithm for combining the information from several mass spectra of the same peptide. The algorithm automatically learns peptide fragmentation patterns, so that...
Ritendra Datta, Marshall W. Bern