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BMCBI
2011
14 years 6 months ago
DoBo: Protein domain boundary prediction by integrating evolutionary signals and machine learning
Background: Accurate identification of protein domain boundaries is useful for protein structure determination and prediction. However, predicting protein domain boundaries from a...
Jesse Eickholt, Xin Deng, Jianlin Cheng
BMCBI
2010
103views more  BMCBI 2010»
14 years 11 months ago
Nonparametric methods for the analysis of single-color pathogen microarrays
Background: The analysis of oligonucleotide microarray data in pathogen surveillance and discovery is a challenging task. Target template concentration, nucleic acid integrity, an...
Omar J. Jabado, Sean Conlan, P. Lan Quan, Jeffrey ...
GCB
2004
Springer
139views Biometrics» more  GCB 2004»
15 years 5 months ago
Conserved RNA Pseudoknots
: Pseudoknots are essential for the functioning of many small RNA molecules. In addition, viral RNAs often exhibit pseudoknots that are required at various stages of the viral life...
C. Thurner, Ivo L. Hofacker, Peter F. Stadler
BMCBI
2006
166views more  BMCBI 2006»
14 years 11 months ago
SEQOPTICS: a protein sequence clustering system
Background: Protein sequence clustering has been widely used as a part of the analysis of protein structure and function. In most cases single linkage or graph-based clustering al...
Yonghui Chen, Kevin D. Reilly, Alan P. Sprague, Zh...
CVPR
2010
IEEE
14 years 9 months ago
Multi-structure model selection via kernel optimisation
Our goal is to fit the multiple instances (or structures) of a generic model existing in data. Here we propose a novel model selection scheme to estimate the number of genuine str...
Tat-Jun Chin, David Suter, Hanzi Wang