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» Multiple alignment by aligning alignments
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167
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BMCBI
2010
143views more  BMCBI 2010»
15 years 1 months ago
A genome alignment algorithm based on compression
Background: Traditional genome alignment methods consider sequence alignment as a variation of the string edit distance problem, and perform alignment by matching characters of th...
Minh Duc Cao, Trevor I. Dix, Lloyd Allison
157
Voted
BIOINFORMATICS
2011
14 years 10 months ago
Integrative network alignment reveals large regions of global network similarity in yeast and human
Motivation: High-throughput methods for detecting molecular interactions have produced large sets of biological network data with much more yet to come. Analogous to sequence alig...
Oleksii Kuchaiev, Natasa Przulj
132
Voted
ACL
2012
13 years 6 months ago
Learning Better Rule Extraction with Translation Span Alignment
This paper presents an unsupervised approach to learning translation span alignments from parallel data that improves syntactic rule extraction by deleting spurious word alignment...
Jingbo Zhu, Tong Xiao, Chunliang Zhang
111
Voted
BMCBI
2008
86views more  BMCBI 2008»
15 years 3 months ago
Subfamily specific conservation profiles for proteins based on n-gram patterns
Background: A new algorithm has been developed for generating conservation profiles that reflect the evolutionary history of the subfamily associated with a query sequence. It is ...
John K. Vries, Xiong Liu
IPPS
2006
IEEE
15 years 9 months ago
A method to improve structural modeling based on conserved domain clusters
—Homology modeling requires an accurate alignment between a query sequence and its homologs with known three-dimensional (3D) information. Current structural modeling techniques ...
Fa Zhang, Lin Xu, Bo Yuan