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ACL
2012
13 years 6 months ago
Improving the IBM Alignment Models Using Variational Bayes
Bayesian approaches have been shown to reduce the amount of overfitting that occurs when running the EM algorithm, by placing prior probabilities on the model parameters. We appl...
Darcey Riley, Daniel Gildea
BIBM
2008
IEEE
112views Bioinformatics» more  BIBM 2008»
15 years 10 months ago
Fast Alignments of Metabolic Networks
Network alignments are extensively used for comparing, exploring, and predicting biological networks. Existing alignment tools are mostly based on isomorphic and homeomorphic embe...
Qiong Cheng, Piotr Berman, Robert W. Harrison, Ale...
ICASSP
2007
IEEE
15 years 10 months ago
Protein Fold Recognition using Residue-Based Alignments of Sequence and Secondary Structure
Protein structure prediction aims to determine the three-dimensional structure of proteins form their amino acid sequences. When a protein does not have similarity (homology) to a...
Zafer Aydin, Hakan Erdogan, Yucel Altunbasak
119
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RECOMB
2010
Springer
15 years 9 months ago
SubMAP: Aligning Metabolic Pathways with Subnetwork Mappings
Abstract. We consider the problem of aligning two metabolic pathways. Unlike traditional approaches, we do not restrict the alignment to one-to-one mappings between the molecules o...
Ferhat Ay, Tamer Kahveci
BMCBI
2010
89views more  BMCBI 2010»
15 years 4 months ago
Enhancing metabolomic data analysis with Progressive Consensus Alignment of NMR Spectra (PCANS)
Background: Nuclear magnetic resonance spectroscopy is one of the primary tools in metabolomics analyses, where it is used to track and quantify changes in metabolite concentratio...
Jennifer M. Staab, Thomas M. O'Connell, Shawn M. G...