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2010
Springer
15 years 1 months ago
Improving Multi-Relief for Detecting Specificity Residues from Multiple Sequence Alignments
A challenging problem in bioinformatics is the detection of residues that account for protein function specificity, not only in order to gain deeper insight in the nature of functi...
Elena Marchiori
BMCBI
2008
94views more  BMCBI 2008»
14 years 9 months ago
Identification of Proteins Secreted by Malaria Parasite into Erythrocyte using SVM and PSSM profiles
Background: Malaria parasite secretes various proteins in infected RBC for its growth and survival. Thus identification of these secretory proteins is important for developing vac...
Ruchi Verma, Ajit Tiwari, Sukhwinder Kaur, Grish C...
BMCBI
2004
177views more  BMCBI 2004»
14 years 9 months ago
Gapped alignment of protein sequence motifs through Monte Carlo optimization of a hidden Markov model
Background: Certain protein families are highly conserved across distantly related organisms and belong to large and functionally diverse superfamilies. The patterns of conservati...
Andrew F. Neuwald, Jun S. Liu
BMCBI
2006
139views more  BMCBI 2006»
14 years 9 months ago
Improvement in accuracy of multiple sequence alignment using novel group-to-group sequence alignment algorithm with piecewise li
Background: Multiple sequence alignment (MSA) is a useful tool in bioinformatics. Although many MSA algorithms have been developed, there is still room for improvement in accuracy...
Shinsuke Yamada, Osamu Gotoh, Hayato Yamana
NAR
2007
136views more  NAR 2007»
14 years 9 months ago
DBAli tools: mining the protein structure space
The DBAli tools use a comprehensive set of structural alignments in the DBAli database to leverage the structural information deposited in the Protein Data Bank (PDB). These tools...
Marc A. Martí-Renom, Ursula Pieper, Mallur ...