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BMCBI
2010
171views more  BMCBI 2010»
15 years 24 days ago
PyMix - The Python mixture package - a tool for clustering of heterogeneous biological data
Background: Cluster analysis is an important technique for the exploratory analysis of biological data. Such data is often high-dimensional, inherently noisy and contains outliers...
Benjamin Georgi, Ivan Gesteira Costa, Alexander Sc...
116
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BMCBI
2010
104views more  BMCBI 2010»
15 years 24 days ago
Parameters for accurate genome alignment
Background: Genome sequence alignments form the basis of much research. Genome alignment depends on various mundane but critical choices, such as how to mask repeats and which sco...
Martin C. Frith, Michiaki Hamada, Paul Horton
141
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BMCBI
2010
133views more  BMCBI 2010»
15 years 24 days ago
Consolidating metabolite identifiers to enable contextual and multi-platform metabolomics data analysis
Background: Analysis of data from high-throughput experiments depends on the availability of well-structured data that describe the assayed biomolecules. Procedures for obtaining ...
Henning Redestig, Miyako Kusano, Atsushi Fukushima...
133
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BMCBI
2010
143views more  BMCBI 2010»
15 years 24 days ago
ETE: a python Environment for Tree Exploration
Background: Many bioinformatics analyses, ranging from gene clustering to phylogenetics, produce hierarchical trees as their main result. These are used to represent the relations...
Jaime Huerta-Cepas, Joaquín Dopazo, Toni Ga...
105
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BMCBI
2010
124views more  BMCBI 2010»
15 years 24 days ago
Estimation and efficient computation of the true probability of recurrence of short linear protein sequence motifs in unrelated
Background: Large datasets of protein interactions provide a rich resource for the discovery of Short Linear Motifs (SLiMs) that recur in unrelated proteins. However, existing met...
Norman E. Davey, Richard J. Edwards, Denis C. Shie...