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BMCBI
2007
246views more  BMCBI 2007»
15 years 23 days ago
TomoJ: tomography software for three-dimensional reconstruction in transmission electron microscopy
Background: Transmission electron tomography is an increasingly common three-dimensional electron microscopy approach that can provide new insights into the structure of subcellul...
Cédric Messaoudi, Thomas Boudier, Carlos Os...
BMCBI
2008
105views more  BMCBI 2008»
15 years 22 days ago
A Bayesian method for calculating real-time quantitative PCR calibration curves using absolute plasmid DNA standards
Background: In real-time quantitative PCR studies using absolute plasmid DNA standards, a calibration curve is developed to estimate an unknown DNA concentration. However, potenti...
Mano Sivaganesan, Shawn Seifring, Manju Varma, Ric...
BMCBI
2008
122views more  BMCBI 2008»
15 years 22 days ago
High-throughput bioinformatics with the Cyrille2 pipeline system
Background: Modern omics research involves the application of high-throughput technologies that generate vast volumes of data. These data need to be pre-processed, analyzed and in...
Mark W. E. J. Fiers, Ate van der Burgt, Erwin Date...
127
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BMCBI
2008
178views more  BMCBI 2008»
15 years 22 days ago
A discriminative method for protein remote homology detection and fold recognition combining Top-n-grams and latent semantic ana
Background: Protein remote homology detection and fold recognition are central problems in bioinformatics. Currently, discriminative methods based on support vector machine (SVM) ...
Bin Liu, Xiaolong Wang, Lei Lin, Qiwen Dong, Xuan ...
BMCBI
2008
323views more  BMCBI 2008»
15 years 22 days ago
A compatible exon-exon junction database for the identification of exon skipping events using tandem mass spectrum data
Background: Alternative splicing is an important gene regulation mechanism. It is estimated that about 74% of multi-exon human genes have alternative splicing. High throughput tan...
Fan Mo, Xu Hong, Feng Gao, Lin Du, Jun Wang, Gilbe...