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» Multiplicative Background Risk
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122
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BMCBI
2002
133views more  BMCBI 2002»
15 years 12 days ago
Identification and characterization of subfamily-specific signatures in a large protein superfamily by a hidden Markov model app
Background: Most profile and motif databases strive to classify protein sequences into a broad spectrum of protein families. The next step of such database studies should include ...
Kevin Truong, Mitsuhiko Ikura
125
Voted
BMCBI
2010
153views more  BMCBI 2010»
14 years 11 months ago
DiffCoEx: a simple and sensitive method to find differentially coexpressed gene modules
Background: Large microarray datasets have enabled gene regulation to be studied through coexpression analysis. While numerous methods have been developed for identifying differen...
Bruno M. Tesson, Rainer Breitling, Ritsert C. Jans...
109
Voted
JSAC
2010
135views more  JSAC 2010»
14 years 11 months ago
Provisioning mission-critical telerobotic control systems over internet backbone networks with essentially-perfect QoS
—Over the next decades, the Internet will evolve to support increasingly complex mission-critical services such as telerobotically controlled surgery. The world’s first telero...
T. H. Szymanski, D. Gilbert
BMCBI
2010
126views more  BMCBI 2010»
14 years 10 months ago
Systematic integration of experimental data and models in systems biology
Background: The behaviour of biological systems can be deduced from their mathematical models. However, multiple sources of data in diverse forms are required in the construction ...
Peter Li, Joseph O. Dada, Daniel Jameson, Irena Sp...
BMCBI
2010
155views more  BMCBI 2010»
14 years 10 months ago
BrEPS: a flexible and automatic protocol to compute enzyme-specific sequence profiles for functional annotation
Background: Models for the simulation of metabolic networks require the accurate prediction of enzyme function. Based on a genomic sequence, enzymatic functions of gene products a...
Constantin Bannert, A. Welfle, C. aus dem Spring, ...