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» Multiplicative Background Risk
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87
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BMCBI
2010
106views more  BMCBI 2010»
15 years 19 days ago
Selection of optimal reference genes for normalization in quantitative RT-PCR
Background: Normalization in real-time qRT-PCR is necessary to compensate for experimental variation. A popular normalization strategy employs reference gene(s), which may introdu...
Inna Chervoneva, Yanyan Li, Stephanie Schulz, Sean...
BMCBI
2010
149views more  BMCBI 2010»
15 years 19 days ago
Identifying common prognostic factors in genomic cancer studies: A novel index for censored outcomes
Background: With the growing number of public repositories for high-throughput genomic data, it is of great interest to combine the results produced by independent research groups...
Sigrid Rouam, Thierry Moreau, Philippe Broët
121
Voted
BMCBI
2010
126views more  BMCBI 2010»
15 years 19 days ago
A boosting method for maximizing the partial area under the ROC curve
Background: The receiver operating characteristic (ROC) curve is a fundamental tool to assess the discriminant performance for not only a single marker but also a score function c...
Osamu Komori, Shinto Eguchi
93
Voted
BMCBI
2010
208views more  BMCBI 2010»
15 years 19 days ago
A multi-filter enhanced genetic ensemble system for gene selection and sample classification of microarray data
Background: Feature selection techniques are critical to the analysis of high dimensional datasets. This is especially true in gene selection from microarray data which are common...
Pengyi Yang, Bing Bing Zhou, Zili Zhang, Albert Y....
105
Voted
BMCBI
2010
84views more  BMCBI 2010»
15 years 19 days ago
An integrated analysis of molecular aberrations in NCI-60 cell lines
Background: Cancer is a complex disease where various types of molecular aberrations drive the development and progression of malignancies. Large-scale screenings of multiple type...
Chen-Hsiang Yeang