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119
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BMCBI
2010
118views more  BMCBI 2010»
15 years 3 months ago
Testing for mean and correlation changes in microarray experiments: an application for pathway analysis
Background: Microarray experiments examine the change in transcript levels of tens of thousands of genes simultaneously. To derive meaningful data, biologists investigate the resp...
Mayer Alvo, Zhongzhu Liu, Andrew Williams, Carole ...
134
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BMCBI
2004
106views more  BMCBI 2004»
15 years 3 months ago
Spotting effect in microarray experiments
Background: Microarray data must be normalized because they suffer from multiple biases. We have identified a source of spatial experimental variability that significantly affects...
Tristan Mary-Huard, Jean-Jacques Daudin, Sté...
126
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BMCBI
2008
148views more  BMCBI 2008»
15 years 3 months ago
BATS: a Bayesian user-friendly software for Analyzing Time Series microarray experiments
Summary: BATS is a user-friendly software for Bayesian Analysis of Time Series microarray experiments based on the novel, truly functional and fully Bayesian approach proposed in ...
Claudia Angelini, Luisa Cutillo, Daniela De Candit...
127
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BIOINFORMATICS
2006
89views more  BIOINFORMATICS 2006»
15 years 3 months ago
Maximum significance clustering of oligonucleotide microarrays
Affymetrix high-density oligonucleotide microarrays measure expression of DNA transcripts using probesets, i.e. multiple probes per transcript. Usually, these multiple measurement...
Dick de Ridder, Frank J. T. Staal, Jacques J. M. v...
137
Voted
BMCBI
2008
124views more  BMCBI 2008»
15 years 3 months ago
A probe-treatment-reference (PTR) model for the analysis of oligonucleotide expression microarrays
Background: Microarray pre-processing usually consists of normalization and summarization. Normalization aims to remove non-biological variations across different arrays. The norm...
Huanying Ge, Chao Cheng, Lei M. Li