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BMCBI
2005
14 years 10 months ago
2005
Background: Most proteins function by interacting with other molecules. Their interaction interfaces are highly conserved throughout evolution to avoid undesirable interactions th...
BMCBI
2005
14 years 10 months ago
2005
Background: Recognition codes for protein-DNA interactions typically assume that the interacting positions contribute additively to the binding energy. While this is known to not ...
129
Voted
BMCBI
2005
14 years 10 months ago
2005
Background: The responses to interleukin 1 (IL-1) in human chondrocytes constitute a complex regulatory mechanism, where multiple transcription factors interact combinatorially to...
BMCBI
2005
14 years 10 months ago
2005
Background: Determination and quantification of nucleic acid components in a mixture is usually accomplished by microarray approaches, where the mixtures are hybridized against sp...
83
Voted
BMCBI
2005
14 years 10 months ago
2005
Background: To facilitate efficient selection and the prioritization of candidate complex disease susceptibility genes for association analysis, increasingly comprehensive annotat...