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» NEC for Gene Expression Analysis
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BMCBI
2008
128views more  BMCBI 2008»
14 years 10 months ago
Meta-analysis of breast cancer microarray studies in conjunction with conserved cis-elements suggest patterns for coordinate reg
Background: Gene expression measurements from breast cancer (BrCa) tumors are established clinical predictive tools to identify tumor subtypes, identify patients showing poor/good...
David D. Smith, Pål Sætrom, Ola R. Sn&...
ICDE
2004
IEEE
133views Database» more  ICDE 2004»
15 years 11 months ago
GenExplore: Interactive Exploration of Gene Interactions from Microarray Data
DNA Microarray provides a powerful basis for analysis of gene expression. Data mining methods such as clustering have been widely applied to microarray data to link genes that sho...
Yong Ye, Xintao Wu, Kalpathi R. Subramanian, Liyin...
BMCBI
2006
119views more  BMCBI 2006»
14 years 10 months ago
Utilization of two sample t-test statistics from redundant probe sets to evaluate different probe set algorithms in GeneChip stu
Background: The choice of probe set algorithms for expression summary in a GeneChip study has a great impact on subsequent gene expression data analysis. Spiked-in cRNAs with know...
Zihua Hu, Gail R. Willsky
BMCBI
2010
99views more  BMCBI 2010»
14 years 10 months ago
Different effects of the probe summarization algorithms PLIER and RMA on high-level analysis of Affymetrix exon arrays
Background: Alternative splicing is an important mechanism that increases protein diversity and functionality in higher eukaryotes. Affymetrix exon arrays are a commercialized pla...
Yi Qu, Fei He, Yuchen Chen
BMCBI
2008
76views more  BMCBI 2008»
14 years 10 months ago
Empirical Bayes analysis of single nucleotide polymorphisms
Background: An important goal of whole-genome studies concerned with single nucleotide polymorphisms (SNPs) is the identification of SNPs associated with a covariate of interest s...
Holger Schwender, Katja Ickstadt