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BMCBI
2006
122views more  BMCBI 2006»
14 years 10 months ago
Computational reconstruction of transcriptional regulatory modules of the yeast cell cycle
Background: A transcriptional regulatory module (TRM) is a set of genes that is regulated by a common set of transcription factors (TFs). By organizing the genome into TRMs, a liv...
Wei-Sheng Wu, Wen-Hsiung Li, Bor-Sen Chen
CIBCB
2005
IEEE
14 years 11 months ago
A Transcriptional Approach to Gene Clustering
— We present an integrative method for clustering coregulated genes and elucidating their underlying regulatory mechanisms. We use multi-state partition functions and thermodynam...
Ilias Tagkopoulos
BIB
2007
59views more  BIB 2007»
14 years 10 months ago
Statistically designing microarrays and microarray experiments to enhance sensitivity and specificity
Gene expression signatures from microarray experiments promise to provide important prognostic tools for predicting disease outcome or response to treatment. A number of microarra...
Jason C. Hsu, Jane Chang, Tao Wang, Eiríkur...
NAR
2011
191views Computer Vision» more  NAR 2011»
14 years 20 days ago
ConsensusPathDB: toward a more complete picture of cell biology
ConsensusPathDB is a meta-database that integrates different types of functional interactions from heterogeneous interaction data resources. Physical protein interactions, metabol...
Atanas Kamburov, Konstantin Pentchev, Hanna Galick...
BMCBI
2008
118views more  BMCBI 2008»
14 years 10 months ago
PseudoGeneQuest - Service for identification of different pseudogene types in the human genome
Background: Pseudogenes, nonfunctional copies of genes, evolve fast due the lack of evolutionary pressures and thus appear in several different forms. PseudoGeneQuest is an online...
Csaba P. Ortutay, Mauno Vihinen