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NAR
2008
174views more  NAR 2008»
14 years 8 months ago
miRGator: an integrated system for functional annotation of microRNAs
MicroRNAs (miRNAs) constitute an important class of regulators that are involved in various cellular and disease processes. However, the functional significance of each miRNA is m...
Seungyoon Nam, Bumjin Kim, Seokmin Shin, Sanghyuk ...
BMCBI
2005
169views more  BMCBI 2005»
14 years 9 months ago
An adaptive method for cDNA microarray normalization
Background: Normalization is a critical step in analysis of gene expression profiles. For duallabeled arrays, global normalization assumes that the majority of the genes on the ar...
Yingdong Zhao, Ming-Chung Li, Richard Simon
BMCBI
2010
156views more  BMCBI 2010»
14 years 10 months ago
Evaluation of statistical methods for normalization and differential expression in mRNA-Seq experiments
Background: High-throughput sequencing technologies, such as the Illumina Genome Analyzer, are powerful new tools for investigating a wide range of biological and medical question...
James H. Bullard, Elizabeth Purdom, Kasper D. Hans...
BIOSYSTEMS
2008
75views more  BIOSYSTEMS 2008»
14 years 10 months ago
Using matrix of thresholding partial correlation coefficients to infer regulatory network
DNA arrays measure the expression levels for thousands of genes simultaneously under different conditions. These measurements reflect many aspects of the underlying biological pro...
Lide Han, Jun Zhu
ICPR
2008
IEEE
15 years 4 months ago
Gene function prediction using protein domain probability and hierarchical Gene Ontology information
The Gene Ontology (GO) is a controlled vocabulary of terms to describe protein functions. It also includes a hierarchical description of the relationships among the terms in the f...
Jaehee Jung, Michael R. Thon