MicroRNAs (miRNAs) constitute an important class of regulators that are involved in various cellular and disease processes. However, the functional significance of each miRNA is m...
Seungyoon Nam, Bumjin Kim, Seokmin Shin, Sanghyuk ...
Background: Normalization is a critical step in analysis of gene expression profiles. For duallabeled arrays, global normalization assumes that the majority of the genes on the ar...
Background: High-throughput sequencing technologies, such as the Illumina Genome Analyzer, are powerful new tools for investigating a wide range of biological and medical question...
James H. Bullard, Elizabeth Purdom, Kasper D. Hans...
DNA arrays measure the expression levels for thousands of genes simultaneously under different conditions. These measurements reflect many aspects of the underlying biological pro...
The Gene Ontology (GO) is a controlled vocabulary of terms to describe protein functions. It also includes a hierarchical description of the relationships among the terms in the f...