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BMCBI
2005
121views more  BMCBI 2005»
14 years 9 months ago
Comparison of seven methods for producing Affymetrix expression scores based on False Discovery Rates in disease profiling data
Background: A critical step in processing oligonucleotide microarray data is combining the information in multiple probes to produce a single number that best captures the express...
Kerby Shedden, Wei Chen, Rork Kuick, Debashis Ghos...
BCB
2010
138views Bioinformatics» more  BCB 2010»
14 years 4 months ago
Comparative analysis of biclustering algorithms
Biclustering is a very popular method to identify hidden co-regulation patterns among genes. There are numerous biclustering algorithms designed to undertake this challenging task...
Doruk Bozdag, Ashwin S. Kumar, Ümit V. &Ccedi...
BMCBI
2008
122views more  BMCBI 2008»
14 years 10 months ago
OpenDMAP: An open source, ontology-driven concept analysis engine, with applications to capturing knowledge regarding protein tr
Background: Information extraction (IE) efforts are widely acknowledged to be important in harnessing the rapid advance of biomedical knowledge, particularly in areas where import...
Lawrence Hunter, Zhiyong Lu, James Firby, William ...
BMCBI
2010
160views more  BMCBI 2010»
14 years 10 months ago
Quantitative model for inferring dynamic regulation of the tumour suppressor gene p53
Background: The availability of various "omics" datasets creates a prospect of performing the study of genomewide genetic regulatory networks. However, one of the major ...
Junbai Wang, Tianhai Tian
BMCBI
2010
110views more  BMCBI 2010»
14 years 10 months ago
TimeDelay-ARACNE: Reverse engineering of gene networks from time-course data by an information theoretic approach
Background: One of main aims of Molecular Biology is the gain of knowledge about how molecular components interact each other and to understand gene function regulations. Using mi...
Pietro Zoppoli, Sandro Morganella, Michele Ceccare...