Genetical genomics has been established to study genetic variation of gene expression. It treats transcript expression as a quantitative trait and identifies putative regulatory l...
Jung Hoon Woo, Eunjee Lee, Sung-Bum Cho, Ju Han Ki...
: Despite recent advances in DNA chip technology current microarray gene expression studies are still affected by high noise levels, small sample sizes and large numbers of uninfor...
Enrico Glaab, Jonathan M. Garibaldi, Natalio Krasn...
Background: Methylation of CpG islands within the DNA promoter regions is one mechanism that leads to aberrant gene expression in cancer. In particular, the abnormal methylation o...
Leandro A. Loss, Anguraj Sadanandam, Steffen Durin...
Background: The evolution of high throughput technologies that measure gene expression levels has created a data base for inferring GRNs (a process also known as reverse engineeri...
Background: The biological interpretation of large-scale gene expression data is one of the paramount challenges in current bioinformatics. In particular, placing the results in t...