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BMCBI
2010
14 years 9 months ago
2010
Background: Protein loops encompass 50% of protein residues in available three-dimensional structures. These regions are often involved in protein functions, e.g. binding site, ca...
BMCBI
2010
14 years 9 months ago
2010
Background: Considering energy function to detect a correct protein fold from incorrect ones is very important for protein structure prediction and protein folding. Knowledge-base...
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BMCBI
2010
14 years 9 months ago
2010
Background: Predicting which molecules can bind to a given binding site of a protein with known 3D structure is important to decipher the protein function, and useful in drug desi...
123
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BMCBI
2007
14 years 9 months ago
2007
Background: Designing appropriate machine learning methods for identifying genes that have a significant discriminating power for disease outcomes has become more and more importa...
BMCBI
2008
14 years 9 months ago
2008
Background: The topology of signaling cascades has been studied in quite some detail. However, how information is processed exactly is still relatively unknown. Since quite divers...