— Microarray technology offers a high throughput means to study expression networks and gene regulatory networks in cells. The intrinsic nature of high dimensionality and small s...
Yijuan Lu, Qi Tian, Maribel Sanchez, Jennifer L. N...
Background: Genome-wide expression signatures are emerging as potential marker for overall survival and disease recurrence risk as evidenced by recent commercialization of gene ex...
Samir B. Amin, Parantu K. Shah, Aimin Yan, Sophia ...
Background: Identification of transcription factors (TFs) involved in a biological process is the first step towards a better understanding of the underlying regulatory mechanisms...
Xiaoqi Cui, Tong Wang, Huann-Sheng Chen, Victor Bu...
Background: Reconstructing regulatory networks from gene expression profiles is a challenging problem of functional genomics. In microarray studies the number of samples is often ...
Barbara Di Camillo, Fatima Sanchez-Cabo, Gianna To...
Computing methods that allow the efficient and accurate processing of experimentally gathered data play a crucial role in biological research. The aim of this paper is to present a...