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» Network constrained clustering for gene microarray data
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ICDM
2008
IEEE
146views Data Mining» more  ICDM 2008»
15 years 4 months ago
Hunting for Coherent Co-clusters in High Dimensional and Noisy Datasets
Clustering problems often involve datasets where only a part of the data is relevant to the problem, e.g., in microarray data analysis only a subset of the genes show cohesive exp...
Meghana Deodhar, Joydeep Ghosh, Gunjan Gupta, Hyuk...
BMCBI
2006
127views more  BMCBI 2006»
14 years 9 months ago
Using local gene expression similarities to discover regulatory binding site modules
Background: We present an approach designed to identify gene regulation patterns using sequence and expression data collected for Saccharomyces cerevisae. Our main goal is to rela...
Bartek Wilczynski, Torgeir R. Hvidsten, Andriy Kry...
BMCBI
2007
182views more  BMCBI 2007»
14 years 9 months ago
Identifying regulatory targets of cell cycle transcription factors using gene expression and ChIP-chip data
Background: ChIP-chip data, which indicate binding of transcription factors (TFs) to DNA regions in vivo, are widely used to reconstruct transcriptional regulatory networks. Howev...
Wei-Sheng Wu, Wen-Hsiung Li, Bor-Sen Chen
FUIN
2007
109views more  FUIN 2007»
14 years 9 months ago
Unifying Framework for Rule Semantics: Application to Gene Expression Data
Abstract. The notion of rules is very popular and appears in different flavors, for example as association rules in data mining or as functional dependencies in databases. Their s...
Marie Agier, Jean-Marc Petit, Einoshin Suzuki
BMCBI
2008
166views more  BMCBI 2008»
14 years 9 months ago
Learning transcriptional regulatory networks from high throughput gene expression data using continuous three-way mutual informa
Background: Probability based statistical learning methods such as mutual information and Bayesian networks have emerged as a major category of tools for reverse engineering mecha...
Weijun Luo, Kurt D. Hankenson, Peter J. Woolf