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» Network constrained clustering for gene microarray data
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BMCBI
2010
96views more  BMCBI 2010»
14 years 9 months ago
QTLminer: identifying genes regulating quantitative traits
Background: Quantitative trait locus (QTL) mapping identifies genomic regions that likely contain genes regulating a quantitative trait. However, QTL regions may encompass tens to...
Rudi Alberts, Klaus Schughart
NN
2007
Springer
267views Neural Networks» more  NN 2007»
14 years 9 months ago
Modeling of gene regulatory networks with hybrid differential evolution and particle swarm optimization
In the last decade, recurrent neural networks (RNNs) have attracted more efforts in inferring genetic regulatory networks (GRNs), using time series gene expression data from micro...
Rui Xu, Ganesh K. Venayagamoorthy, Donald C. Wunsc...
BMCBI
2004
146views more  BMCBI 2004»
14 years 9 months ago
Defining transcriptional networks through integrative modeling of mRNA expression and transcription factor binding data
Background: Functional genomics studies are yielding information about regulatory processes in the cell at an unprecedented scale. In the yeast S. cerevisiae, DNA microarrays have...
Feng Gao, Barrett C. Foat, Harmen J. Bussemaker
BMCBI
2005
122views more  BMCBI 2005»
14 years 9 months ago
A microarray data-based semi-kinetic method for predicting quantitative dynamics of genetic networks
Background: Elucidating the dynamic behaviour of genetic regulatory networks is one of the most significant challenges in systems biology. However, conventional quantitative predi...
Katsuyuki Yugi, Yoichi Nakayama, Shigen Kojima, To...
SDM
2004
SIAM
162views Data Mining» more  SDM 2004»
14 years 11 months ago
Subspace Clustering of High Dimensional Data
Clustering suffers from the curse of dimensionality, and similarity functions that use all input features with equal relevance may not be effective. We introduce an algorithm that...
Carlotta Domeniconi, Dimitris Papadopoulos, Dimitr...