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» Network constrained clustering for gene microarray data
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JMLR
2006
103views more  JMLR 2006»
14 years 9 months ago
MinReg: A Scalable Algorithm for Learning Parsimonious Regulatory Networks in Yeast and Mammals
In recent years, there has been a growing interest in applying Bayesian networks and their extensions to reconstruct regulatory networks from gene expression data. Since the gene ...
Dana Pe'er, Amos Tanay, Aviv Regev
BIOINFORMATICS
2010
109views more  BIOINFORMATICS 2010»
14 years 9 months ago
Phylogenetic networks do not need to be complex: using fewer reticulations to represent conflicting clusters
Phylogenetic trees are widely used to display estimates of how groups of species evolved. Each phylogenetic tree can be seen as a collection of clusters, subgroups of the species ...
Leo van Iersel, Steven Kelk, Regula Rupp, Daniel H...
RECOMB
2003
Springer
15 years 10 months ago
Physical network models and multi-source data integration
We develop a new framework for inferring models of transcriptional regulation. The models in this approach, which we call physical models, are constructed on the basis of verifiab...
Chen-Hsiang Yeang, Tommi Jaakkola
63
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BMCBI
2002
89views more  BMCBI 2002»
14 years 9 months ago
Sources of variability and effect of experimental approach on expression profiling data interpretation
Background: We provide a systematic study of the sources of variability in expression profiling data using 56 RNAs isolated from human muscle biopsies (34 Affymetrix MuscleChip ar...
Marina Bakay, Yi-Wen Chen, Rehannah H. A. Borup, P...
73
Voted
CEC
2005
IEEE
15 years 3 months ago
Clustering-based approach to identify solutions for the inference of regulatory networks
Abstract- In this paper we address the problem of finding valid solutions for the problem of inferring gene regulatory networks. Different approaches to directly infer the depende...
Christian Spieth, Felix Streichert, Nora Speer, An...