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» Network constrained clustering for gene microarray data
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BMCBI
2007
162views more  BMCBI 2007»
14 years 9 months ago
Genome-wide identification of specific oligonucleotides using artificial neural network and computational genomic analysis
Background: Genome-wide identification of specific oligonucleotides (oligos) is a computationallyintensive task and is a requirement for designing microarray probes, primers, and ...
Chun-Chi Liu, Chin-Chung Lin, Ker-Chau Li, Wen-Shy...
BMCBI
2006
180views more  BMCBI 2006»
14 years 9 months ago
The Gaggle: An open-source software system for integrating bioinformatics software and data sources
Background: Systems biologists work with many kinds of data, from many different sources, using a variety of software tools. Each of these tools typically excels at one type of an...
Paul T. Shannon, David J. Reiss, Richard Bonneau, ...
BIOINFORMATICS
2006
118views more  BIOINFORMATICS 2006»
14 years 9 months ago
A probabilistic dynamical model for quantitative inference of the regulatory mechanism of transcription
Motivation Quantitative estimation of the regulatory relationship between transcription factors and genes is a fundamental stepping stone when trying to develop models of cellular...
Guido Sanguinetti, Magnus Rattray, Neil D. Lawrenc...
86
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KDD
2007
ACM
159views Data Mining» more  KDD 2007»
15 years 10 months ago
Constraint-driven clustering
Clustering methods can be either data-driven or need-driven. Data-driven methods intend to discover the true structure of the underlying data while need-driven methods aims at org...
Rong Ge, Martin Ester, Wen Jin, Ian Davidson
99
Voted
BMCBI
2007
186views more  BMCBI 2007»
14 years 9 months ago
Modeling human cancer-related regulatory modules by GA-RNN hybrid algorithms
Background: Modeling cancer-related regulatory modules from gene expression profiling of cancer tissues is expected to contribute to our understanding of cancer biology as well as...
Jung-Hsien Chiang, Shih-Yi Chao