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BMCBI
2007
101views more  BMCBI 2007»
14 years 11 months ago
Gene expression changes induced by the tumorigenic pyrrolizidine alkaloid riddelliine in liver of Big Blue rats
Background: Pyrrolizidine alkaloids (PAs) are probably the most common plant constituents that poison livestock, wildlife, and humans worldwide. Riddelliine is isolated from plant...
Nan Mei, Lei Guo, Ruqing Liu, James C. Fuscoe, Tao...
BMCBI
2007
168views more  BMCBI 2007»
14 years 11 months ago
Bayesian model-based inference of transcription factor activity
Background: In many approaches to the inference and modeling of regulatory interactions using microarray data, the expression of the gene coding for the transcription factor is co...
Simon Rogers, Raya Khanin, Mark Girolami
BMCBI
2007
122views more  BMCBI 2007»
14 years 11 months ago
Dissecting complex transcriptional responses using pathway-level scores based on prior information
Background: The genomewide pattern of changes in mRNA expression measured using DNA microarrays is typically a complex superposition of the response of multiple regulatory pathway...
Harmen J. Bussemaker, Lucas D. Ward, André ...
BMCBI
2007
209views more  BMCBI 2007»
14 years 11 months ago
SYMBIOmatics: Synergies in Medical Informatics and Bioinformatics - exploring current scientific literature for emerging topics
Background: The SYMBIOmatics Specific Support Action (SSA) is "an information gathering and dissemination activity" that seeks "to identify synergies between the bi...
Dietrich Rebholz-Schuhmann, Graham Cameron, Domini...
BMCBI
2007
177views more  BMCBI 2007»
14 years 11 months ago
Biowep: a workflow enactment portal for bioinformatics applications
Background: The huge amount of biological information, its distribution over the Internet and the heterogeneity of available software tools makes the adoption of new data integrat...
Paolo Romano 0001, Ezio Bartocci, Guglielmo Bertol...
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