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94
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BMCBI
2010
100views more  BMCBI 2010»
14 years 7 months ago
New insights into protein-protein interaction data lead to increased estimates of the S. cerevisiae interactome size
Background: As protein interactions mediate most cellular mechanisms, protein-protein interaction networks are essential in the study of cellular processes. Consequently, several ...
Laure Sambourg, Nicolas Thierry-Mieg
93
Voted
BMCBI
2010
183views more  BMCBI 2010»
14 years 7 months ago
The complexity of gene expression dynamics revealed by permutation entropy
Background: High complexity is considered a hallmark of living systems. Here we investigate the complexity of temporal gene expression patterns using the concept of Permutation En...
Xiaoliang Sun, Yong Zou, Victoria J. Nikiforova, J...
BMCBI
2010
161views more  BMCBI 2010»
14 years 7 months ago
LTC: a novel algorithm to improve the efficiency of contig assembly for physical mapping in complex genomes
Background: Physical maps are the substrate of genome sequencing and map-based cloning and their construction relies on the accurate assembly of BAC clones into large contigs that...
Zeev Frenkel, Etienne Paux, David I. Mester, Cathe...
111
Voted
BMCBI
2010
126views more  BMCBI 2010»
14 years 7 months ago
PETALS: Proteomic Evaluation and Topological Analysis of a mutated Locus' Signaling
Background: Colon cancer is driven by mutations in a number of genes, the most notorious of which is Apc. Though much of Apc's signaling has been mechanistically identified o...
Gürkan Bebek, Vishal Patel, Mark R. Chance
98
Voted
COMCOM
2010
167views more  COMCOM 2010»
14 years 7 months ago
Effective load for flow-level performance modelling of file transfers in wireless LANs
Today, a wide range of 802.11-based Wireless LANs (WLANs) have become dominant to provide wireless Internet access for file transfers. For engineering purposes, there is a need fo...
Geert Jan Hoekstra, Robert D. van der Mei
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