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» Neural Networks for Determining Protein Specificity and Mult...
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BMCBI
2006
78views more  BMCBI 2006»
13 years 6 months ago
Subfamily logos: visualization of sequence deviations at alignment positions with high information content
Background: Recognition of relevant sequence deviations can be valuable for elucidating functional differences between protein subfamilies. Interesting residues at highly conserve...
Eric Beitz
BMCBI
2005
126views more  BMCBI 2005»
13 years 6 months ago
GANN: Genetic algorithm neural networks for the detection of conserved combinations of features in DNA
Background: The multitude of motif detection algorithms developed to date have largely focused on the detection of patterns in primary sequence. Since sequence-dependent DNA struc...
Robert G. Beiko, Robert L. Charlebois
BMCBI
2004
88views more  BMCBI 2004»
13 years 6 months ago
Coronavirus 3CLpro proteinase cleavage sites: Possible relevance to SARS virus pathology
Background: Despite the passing of more than a year since the first outbreak of Severe Acute Respiratory Syndrome (SARS), efficient counter-measures are still few and many believe...
Lars Kiemer, Ole Lund, Søren Brunak, Nikola...
BMCBI
2011
13 years 1 months ago
DoBo: Protein domain boundary prediction by integrating evolutionary signals and machine learning
Background: Accurate identification of protein domain boundaries is useful for protein structure determination and prediction. However, predicting protein domain boundaries from a...
Jesse Eickholt, Xin Deng, Jianlin Cheng
BMCBI
2006
108views more  BMCBI 2006»
13 years 6 months ago
An improved map of conserved regulatory sites for Saccharomyces cerevisiae
Background: The regulatory map of a genome consists of the binding sites for proteins that determine the transcription of nearby genes. An initial regulatory map for S. cerevisiae...
Kenzie D. MacIsaac, Ting Wang, D. Benjamin Gordon,...