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» New Directions on Agile Methods: A Comparative Analysis
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BMCBI
2011
14 years 1 months ago
SeqGene: a comprehensive software solution for mining exome- and transcriptome- sequencing data
Background: The popularity of massively parallel exome and transcriptome sequencing projects demands new data mining tools with a comprehensive set of features to support a wide r...
Xutao Deng
IJCNN
2008
IEEE
15 years 4 months ago
Learning to select relevant perspective in a dynamic environment
— When an agent observes its environment, there are two important characteristics of the perceived information. One is the relevance of information and the other is redundancy. T...
Zhihui Luo, David A. Bell, Barry McCollum, Qingxia...
BMCBI
2006
134views more  BMCBI 2006»
14 years 10 months ago
Application of machine learning in SNP discovery
Background: Single nucleotide polymorphisms (SNP) constitute more than 90% of the genetic variation, and hence can account for most trait differences among individuals in a given ...
Lakshmi K. Matukumalli, John J. Grefenstette, Davi...
OOPSLA
2004
Springer
15 years 3 months ago
The garbage collection advantage: improving program locality
As improvements in processor speed continue to outpace improvements in cache and memory speed, poor locality increasingly degrades performance. Because copying garbage collectors ...
Xianglong Huang, Stephen M. Blackburn, Kathryn S. ...
BMCBI
2008
92views more  BMCBI 2008»
14 years 10 months ago
Proteochemometric modeling of HIV protease susceptibility
Background: A major obstacle in treatment of HIV is the ability of the virus to mutate rapidly into drug-resistant variants. A method for predicting the susceptibility of mutated ...
Maris Lapinsh, Martin Eklund, Ola Spjuth, Peteris ...