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ESWA
2007
100views more  ESWA 2007»
14 years 11 months ago
Using memetic algorithms with guided local search to solve assembly sequence planning
The goal of assembly planning consists in generating feasible sequences to assemble a product and selecting an efficient assembly sequence from which related constraint factors su...
Hwai-En Tseng, Wen-Pai Wang, Hsun-Yi Shih
BMCBI
2010
148views more  BMCBI 2010»
14 years 11 months ago
Calling SNPs without a reference sequence
Background: The most common application for the next-generation sequencing technologies is resequencing, where short reads from the genome of an individual are aligned to a refere...
Aakrosh Ratan, Yu Zhang, Vanessa M. Hayes, Stephan...
BMCBI
2007
265views more  BMCBI 2007»
14 years 11 months ago
Large scale clustering of protein sequences with FORCE -A layout based heuristic for weighted cluster editing
Background: Detecting groups of functionally related proteins from their amino acid sequence alone has been a long-standing challenge in computational genome research. Several clu...
Tobias Wittkop, Jan Baumbach, Francisco P. Lobo, S...
BMCBI
2008
111views more  BMCBI 2008»
14 years 11 months ago
Probabilistic base calling of Solexa sequencing data
Background: Solexa/Illumina short-read ultra-high throughput DNA sequencing technology produces millions of short tags (up to 36 bases) by parallel sequencing-by-synthesis of DNA ...
Jacques Rougemont, Arnaud Amzallag, Christian Isel...
BMCBI
2006
159views more  BMCBI 2006»
14 years 11 months ago
MultiSeq: unifying sequence and structure data for evolutionary analysis
Background: Since the publication of the first draft of the human genome in 2000, bioinformatic data have been accumulating at an overwhelming pace. Currently, more than 3 million...
Elijah Roberts, John Eargle, Dan Wright, Zaida Lut...