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    BMCBI
    2007
    115views more  BMCBI 2007»
    Local comparison of protein structures highlights cases of convergent evolution in analogous functional sites
    14 years 11 months ago
    Local comparison of protein structures highlights cases of convergent evolution in analogous functional sites
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    Background: We performed an exhaustive search for local structural similarities in an ensemble of non-redundant protein functional sites. With the purpose of finding new examples ...
    Gabriele Ausiello, Daniele Peluso, Allegra Via, Ma...
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    BMCBI
    2010
    162views more  BMCBI 2010»
    SNP-RFLPing 2: an updated and integrated PCR-RFLP tool for SNP genotyping
    14 years 11 months ago
    SNP-RFLPing 2: an updated and integrated PCR-RFLP tool for SNP genotyping
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    Background: PCR-restriction fragment length polymorphism (RFLP) assay is a cost-effective method for SNP genotyping and mutation detection, but the manual mining for restriction e...
    Hsueh-Wei Chang, Yu-Huei Cheng, Li-Yeh Chuang, Che...
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    BMCBI
    2010
    201views more  BMCBI 2010»
    Analysis of X-ray Structures of Matrix Metalloproteinases via Chaotic Map Clustering
    14 years 11 months ago
    Analysis of X-ray Structures of Matrix Metalloproteinases via Chaotic Map Clustering
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    Background: Matrix metalloproteinases (MMPs) are well-known biological targets implicated in tumour progression, homeostatic regulation, innate immunity, impaired delivery of pro-...
    Ilenia Giangreco, Orazio Nicolotti, Angelo Carotti...
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    BMCBI
    2010
    129views more  BMCBI 2010»
    LAITOR - Literature Assistant for Identification of Terms co-Occurrences and Relationships
    14 years 11 months ago
    LAITOR - Literature Assistant for Identification of Terms co-Occurrences and Relationships
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    Background: Biological knowledge is represented in scientific literature that often describes the function of genes/ proteins (bioentities) in terms of their interactions (biointe...
    Adriano Barbosa-Silva, Theodoros G. Soldatos, Ivan...
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    BMCBI
    2007
    122views more  BMCBI 2007»
    TAP score: torsion angle propensity normalization applied to local protein structure evaluation
    14 years 11 months ago
    TAP score: torsion angle propensity normalization applied to local protein structure evaluation
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    Background: Experimentally determined protein structures may contain errors and require validation. Conformational criteria based on the Ramachandran plot are mainly used to disti...
    Silvio C. E. Tosatto, Roberto Battistutta
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