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BMCBI
2010
121views more  BMCBI 2010»
15 years 4 months ago
A Markov blanket-based method for detecting causal SNPs in GWAS
Background: Detecting epistatic interactions associated with complex and common diseases can help to improve prevention, diagnosis and treatment of these diseases. With the develo...
Bing Han, Meeyoung Park, Xue-wen Chen
BMCBI
2007
131views more  BMCBI 2007»
15 years 4 months ago
FUNC: a package for detecting significant associations between gene sets and ontological annotations
Background: Genome-wide expression, sequence and association studies typically yield large sets of gene candidates, which must then be further analysed and interpreted. Informatio...
Kay Prüfer, Bjoern Muetzel, Hong Hai Do, Gunt...
BMCBI
2007
115views more  BMCBI 2007»
15 years 4 months ago
Comparing sequences without using alignments: application to HIV/SIV subtyping
Background: In general, the construction of trees is based on sequence alignments. This procedure, however, leads to loss of informationwhen parts of sequence alignments (for inst...
Gilles Didier, Laurent Debomy, Maude Pupin, Ming Z...
BMCBI
2008
137views more  BMCBI 2008»
15 years 4 months ago
VennMaster: Area-proportional Euler diagrams for functional GO analysis of microarrays
Background: Microarray experiments generate vast amounts of data. The functional context of differentially expressed genes can be assessed by querying the Gene Ontology (GO) datab...
Hans A. Kestler, André Müller, Johann ...
BMCBI
2010
140views more  BMCBI 2010»
15 years 4 months ago
Quantification and deconvolution of asymmetric LC-MS peaks using the bi-Gaussian mixture model and statistical model selection
Background: Liquid chromatography-mass spectrometry (LC-MS) is one of the major techniques for the quantification of metabolites in complex biological samples. Peak modeling is on...
Tianwei Yu, Hesen Peng
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