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125
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BMCBI
2008
15 years 3 months ago
2008
The G-protein coupled receptor (GPCR) superfamily is currently the largest class of therapeutic targets. In silico prediction of interactions between GPCRs and small molecules is ...
151
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BMCBI
2008
15 years 3 months ago
2008
Background: Predictive classification on the base of gene expression profiles appeared recently as an attractive strategy for identifying the biological functions of genes. Gene O...
136
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BMCBI
2008
15 years 3 months ago
2008
Background: Protein domains present some of the most useful information that can be used to understand protein structure and functions. Recent research on protein domain boundary ...
116
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BMCBI
2006
15 years 3 months ago
2006
Background: The majority of peptide bonds in proteins are found to occur in the trans conformation. However, for proline residues, a considerable fraction of Prolyl peptide bonds ...
158
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BMCBI
2007
15 years 3 months ago
2007
Background: Protein remote homology detection is a central problem in computational biology. Most recent methods train support vector machines to discriminate between related and ...