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» New analysis and results for the Frank-Wolfe method
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BMCBI
2005
133views more  BMCBI 2005»
15 years 1 months ago
Ab initio identification of putative human transcription factor binding sites by comparative genomics
Background: Understanding transcriptional regulation of gene expression is one of the greatest challenges of modern molecular biology. A central role in this mechanism is played b...
Davide Corà, Carl Herrmann, Christoph Diete...
HOTOS
2007
IEEE
15 years 5 months ago
HotComments: How to Make Program Comments More Useful?
Program comments have long been used as a common practice for improving inter-programmer communication and code readability, by explicitly specifying programmers' intentions ...
Lin Tan, Ding Yuan, Yuanyuan Zhou
BMCBI
2010
232views more  BMCBI 2010»
15 years 1 months ago
LucidDraw: Efficiently visualizing complex biochemical networks within MATLAB
Background: Biochemical networks play an essential role in systems biology. Rapidly growing network data and e research activities call for convenient visualization tools to aid i...
Sheng He, Juan Mei, Guiyang Shi, Zhengxiang Wang, ...
BMCBI
2007
128views more  BMCBI 2007»
15 years 1 months ago
A robust and efficient algorithm for the shape description of protein structures and its application in predicting ligand bindin
Background: An accurate description of protein shape derived from protein structure is necessary to establish an understanding of protein-ligand interactions, which in turn will l...
Lei Xie, Philip E. Bourne
BIBM
2010
IEEE
156views Bioinformatics» more  BIBM 2010»
14 years 11 months ago
Truncation of protein sequences for fast profile alignment with application to subcellular localization
We have recently found that the computation time of homology-based subcellular localization can be substantially reduced by aligning profiles up to the cleavage site positions of s...
Man-Wai Mak, Wei Wang, Sun-Yuan Kung