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» New analysis and results for the Frank-Wolfe method
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BMCBI
2005
133views more  BMCBI 2005»
14 years 9 months ago
Ab initio identification of putative human transcription factor binding sites by comparative genomics
Background: Understanding transcriptional regulation of gene expression is one of the greatest challenges of modern molecular biology. A central role in this mechanism is played b...
Davide Corà, Carl Herrmann, Christoph Diete...
HOTOS
2007
IEEE
15 years 1 months ago
HotComments: How to Make Program Comments More Useful?
Program comments have long been used as a common practice for improving inter-programmer communication and code readability, by explicitly specifying programmers' intentions ...
Lin Tan, Ding Yuan, Yuanyuan Zhou
BMCBI
2010
232views more  BMCBI 2010»
14 years 10 months ago
LucidDraw: Efficiently visualizing complex biochemical networks within MATLAB
Background: Biochemical networks play an essential role in systems biology. Rapidly growing network data and e research activities call for convenient visualization tools to aid i...
Sheng He, Juan Mei, Guiyang Shi, Zhengxiang Wang, ...
BMCBI
2007
128views more  BMCBI 2007»
14 years 9 months ago
A robust and efficient algorithm for the shape description of protein structures and its application in predicting ligand bindin
Background: An accurate description of protein shape derived from protein structure is necessary to establish an understanding of protein-ligand interactions, which in turn will l...
Lei Xie, Philip E. Bourne
BIBM
2010
IEEE
156views Bioinformatics» more  BIBM 2010»
14 years 7 months ago
Truncation of protein sequences for fast profile alignment with application to subcellular localization
We have recently found that the computation time of homology-based subcellular localization can be substantially reduced by aligning profiles up to the cleavage site positions of s...
Man-Wai Mak, Wei Wang, Sun-Yuan Kung