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» New developments in the InterPro database
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BMCBI
2008
141views more  BMCBI 2008»
14 years 11 months ago
The development of PIPA: an integrated and automated pipeline for genome-wide protein function annotation
Background: Automated protein function prediction methods are needed to keep pace with high-throughput sequencing. With the existence of many programs and databases for inferring ...
Chenggang Yu, Nela Zavaljevski, Valmik Desai, Seth...
CIBCB
2006
IEEE
15 years 5 months ago
E2D: A Novel Tool for Annotating Protein Domains in Expressed Sequence Tags
The vast number of expressed sequence tags (ESTs) in public databases provides an important resource for comparative and functional genomics. A variety of methods based on homology...
Guo-Hsing Lee, Nai-Yu Chuang, Wen-Dar Lin, Chung-D...
BMCBI
2002
133views more  BMCBI 2002»
14 years 11 months ago
Identification and characterization of subfamily-specific signatures in a large protein superfamily by a hidden Markov model app
Background: Most profile and motif databases strive to classify protein sequences into a broad spectrum of protein families. The next step of such database studies should include ...
Kevin Truong, Mitsuhiko Ikura
BMCBI
2010
112views more  BMCBI 2010»
14 years 11 months ago
PhenoFam-gene set enrichment analysis through protein structural information
Background: With the current technological advances in high-throughput biology, the necessity to develop tools that help to analyse the massive amount of data being generated is e...
Maciej Paszkowski-Rogacz, Mikolaj Slabicki, M. Ter...
BMCBI
2005
150views more  BMCBI 2005»
14 years 11 months ago
Discover protein sequence signatures from protein-protein interaction data
Background: The development of high-throughput technologies such as yeast two-hybrid systems and mass spectrometry technologies has made it possible to generate large protein-prot...
Jianwen Fang, Ryan J. Haasl, Yinghua Dong, Gerald ...