23 search results - page 4 / 5 » Non-additivity in protein-DNA binding |
BMCBI
2010
14 years 9 months ago
2010
Background: Biological evolution conserves protein residues that are important for structure and function. Both protein stability and function often require a certain degree of st...
IJCNN
2006
IEEE
15 years 3 months ago
2006
IEEE
— The ability to identify protein binding sites and to detect specific amino acid residues that contribute to the specificity and affinity of protein interactions has importan...
104
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BMCBI
2010
14 years 9 months ago
2010
Background: Development of high-throughput methods for measuring DNA interactions of transcription factors together with computational advances in short motif inference algorithms...
BMCBI
2010
14 years 9 months ago
2010
Background: Chromatin immunoprecipitation followed by microarray hybridization (ChIP-chip) is used to study protein-DNA interactions and histone modifications on a genome-scale. T...
125
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BMCBI
2005
14 years 9 months ago
2005
Background: The multitude of motif detection algorithms developed to date have largely focused on the detection of patterns in primary sequence. Since sequence-dependent DNA struc...