Background: Identifying cis-regulatory elements is crucial to understanding gene expression, which highlights the importance of the computational detection of overrepresented tran...
We propose a scheme to introduce directionality in the Random Walker algorithm for image segmentation. In particular, we extend the optimization framework of this algorithm to com...
Background: The modeling of dynamic systems requires estimating kinetic parameters from experimentally measured time-courses. Conventional global optimization methods used for par...
The performance of many supervised and unsupervised learning algorithms is very sensitive to the choice of an appropriate distance metric. Previous work in metric learning and ada...
Background: The ever increasing sizes of population genetic datasets pose great challenges for population structure analysis. The Tracy-Widom (TW) statistical test is widely used ...