16513 search results - page 2769 / 3303 » Numerical Analysis Methods |
195
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BMCBI
2005
15 years 7 months ago
2005
Background: Protein sequence alignments have become indispensable for virtually any evolutionary, structural or functional study involving proteins. Modern sequence search and com...
207
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BMCBI
2005
15 years 7 months ago
2005
Background: The functional sites of a protein present important information for determining its cellular function and are fundamental in drug design. Accordingly, accurate methods...
209
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BMCBI
2005
2005
Phylogenetic reconstruction of ancestral character states for gene expression and mRNA splicing data
15 years 7 months ago
Background: As genomes evolve after speciation, gene content, coding sequence, gene expression, and splicing all diverge with time from ancestors with close relatives. A minimum e...
194
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BMCBI
2005
15 years 7 months ago
2005
Background: High quality sequence alignments of RNA and DNA sequences are an important prerequisite for the comparative analysis of genomic sequence data. Nucleic acid sequences, ...
202
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BMCBI
2005
15 years 7 months ago
2005
Background: Profile hidden Markov model (HMM) techniques are among the most powerful methods for protein homology detection. Yet, the critical features for successful modelling ar...