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BMCBI
2007
146views more  BMCBI 2007»
15 years 4 months ago
Bayesian hierarchical model for transcriptional module discovery by jointly modeling gene expression and ChIP-chip data
Background: Transcriptional modules (TM) consist of groups of co-regulated genes and transcription factors (TF) regulating their expression. Two high-throughput (HT) experimental ...
Xiangdong Liu, Walter J. Jessen, Siva Sivaganesan,...
BMCBI
2010
146views more  BMCBI 2010»
15 years 4 months ago
Genomic selection and complex trait prediction using a fast EM algorithm applied to genome-wide markers
Background: The information provided by dense genome-wide markers using high throughput technology is of considerable potential in human disease studies and livestock breeding pro...
Ross K. Shepherd, Theo H. E. Meuwissen, John A. Wo...
BMCBI
2008
132views more  BMCBI 2008»
15 years 4 months ago
Exon level integration of proteomics and microarray data
Background: Previous studies comparing quantitative proteomics and microarray data have generally found poor correspondence between the two. We hypothesised that this might in par...
Danny A. Bitton, Michal J. Okoniewski, Yvonne Conn...
BMCBI
2007
106views more  BMCBI 2007»
15 years 4 months ago
In silico identification of NF-kappaB-regulated genes in pancreatic beta-cells
Background: Pancreatic beta-cells are the target of an autoimmune attack in type 1 diabetes mellitus (T1DM). This is mediated in part by cytokines, such as interleukin (IL)-1β an...
Najib Naamane, Jacques van Helden, Decio L. Eiziri...
BMCBI
2010
151views more  BMCBI 2010»
15 years 4 months ago
Data reduction for spectral clustering to analyze high throughput flow cytometry data
Background: Recent biological discoveries have shown that clustering large datasets is essential for better understanding biology in many areas. Spectral clustering in particular ...
Habil Zare, Parisa Shooshtari, Arvind Gupta, Ryan ...
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