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146
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BMCBI
2008
123views more  BMCBI 2008»
15 years 3 months ago
PocketMatch: A new algorithm to compare binding sites in protein structures
Background: Recognizing similarities and deriving relationships among protein molecules is a fundamental requirement in present-day biology. Similarities can be present at various...
Kalidas Yeturu, Nagasuma Chandra
117
Voted
BMCBI
2008
111views more  BMCBI 2008»
15 years 3 months ago
Probabilistic base calling of Solexa sequencing data
Background: Solexa/Illumina short-read ultra-high throughput DNA sequencing technology produces millions of short tags (up to 36 bases) by parallel sequencing-by-synthesis of DNA ...
Jacques Rougemont, Arnaud Amzallag, Christian Isel...
130
Voted
BMCBI
2007
108views more  BMCBI 2007»
15 years 3 months ago
Computer-aided identification of polymorphism sets diagnostic for groups of bacterial and viral genetic variants
Background: Single nucleotide polymorphisms (SNPs) and genes that exhibit presence/absence variation have provided informative marker sets for bacterial and viral genotyping. Iden...
Erin P. Price, John Inman-Bamber, Venugopal Thiruv...
127
Voted
BMCBI
2010
128views more  BMCBI 2010»
15 years 3 months ago
Conserved residue clusters at protein-protein interfaces and their use in binding site identification
Background: Biological evolution conserves protein residues that are important for structure and function. Both protein stability and function often require a certain degree of st...
Mainak Guharoy, Pinak Chakrabarti
BMCBI
2008
156views more  BMCBI 2008»
15 years 3 months ago
ArrayWiki: an enabling technology for sharing public microarray data repositories and meta-analyses
Background: A survey of microarray databases reveals that most of the repository contents and data models are heterogeneous (i.e., data obtained from different chip manufacturers)...
Todd H. Stokes, J. T. Torrance, Henry Li, May D. W...
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